COURSE OVERVIEW
Who is this course for?
This course is suited to anyone new to GC or early in their GC career.
Previous Knowledge
No prior knowledge is required for this course.
What you will learn
- How to set-up a GC system
- Basics of the chromatographic process
- Sample introduction
- Columns and temperature programming
- Measuring and optimising chromatographic parameters
COURSE OUTLINE
Introduction to Gas Chromatography (GC) and Its Applications
- Principles of Gas Chromatography
- Advantages and Limitations of GC
- Common Applications in Various Industries
Sample Preparation for GC Analysis
- Importance of Proper Sample Preparation
- Sample Clean-up Techniques
- Analyte Extraction Methods
- Solvent Selection and Compatibility
Overview of GC Instrumentation and Components
- Capacity Factor, Selectivity, Efficiency, and Resolution
- Types of Carrier Gases (Cylinders vs. Generators)
- Gas Purity and Traps
- Flow Rate Optimization
- Electronic Pneumatic Controllers (EPC)
- Constant Flow vs. Constant Pressure
- Syringes and Injection Techniques
- Injection and Wash Programs
- Split/Splitless Sample Introduction
- Liner Selection and Maintenance
- Alternative Injection Techniques
- Column Dimensions and Chemistries
- Ferrules and Column Protection
- Temperature Programming and Optimization
- Flame Ionization Detector (FID)
- Electron Capture Detector (ECD)
- Thermal Conductivity Detector (TCD)
- Other Common Detectors and Their Applications
- Setup and Start-Up Procedures
- Common Problems and Troubleshooting
- Chromatographic Integration
- Calibration Techniques
- Introduction to System Suitability Testing
The Chromatographic Process
Gas Supply and Flow Control
Autosampler and Injection Systems
Inlet Systems
Column Selection and Optimization
Detectors and Detection Techniques
Instrument Setup and Operation
Data Processing and System Suitability Testing
Q&A and Closing Discussion
- Summary of Key Concepts
- Open Discussion on Challenges Faced in GC and its applications
- Resources for Further Learning